| Name | State | School | Class | Pos. | Year | Round | Team |
| Peyton Alford | TN | Powell | 2016 | LHP | 2021 | Free Agent | Seattle Mariners |
| Trey Cabbage | TN | Grainger | 2015 | 3B | 2015 | 4 | Twins |
| Trevyne Carter | TN | Soddy Daisy | 2016 | OF | 2016 | 11 | Padres |
| Evan Carter | TN | Elizabethton | 2020 | OF | 2020 | 2nd | Texas Rangers |
| Gavin Cross | TN | Tennessee | 2019 | OF | 2022 | 1 | Royals |
| Bryce Denton | TN | Ravenwood | 2015 | 3B | 2015 | 2 | Cardinals |
| Dalton Fowler | TN | Arlington | 2018 | LHP | 2019 | 27th | New York Mets |
| Hunter Goodman | TN | Arlington | 2018 | C | 2021 | 4th | Colorado Rockies |
| Ryder Green | TN | Karns | 2018 | OF | 2018 | 3 | Yankees |
| Robert Hassell III | TN | Independence | 2020 | OF | 2020 | 1st | San Diego Padres |
| Alex Haynes | TN | Knoxville Central | 2016 | RHP | 2019 | 15th | Colorado Rockies |
| Mason Hickman | TN | Pope John Paul II | 2017 | RHP | 2020 | 5th | Cleveland Indians |
| Bryce Jarvis | TN | Brentwood Academy | 2017 | RHP | 2020 | 1st | Arizona Diamondbacks |
| Ben Joyce | TN | Farragut | 2018 | RHP | 2022 | 3 | Angels |
| Cooper Kinney | TN | Baylor | 2021 | 3B | 2021 | Comp Balance A | Tampa Bay Rays |
| Landon Knack | TN | Science Hill | 2015 | RHP | 2020 | 2nd | Los Angeles Dodgers |
| Zach Linginfelter | TN | Sevier County | 2016 | RHP | 2016 | 16 | Yankees |
| Guy Lipscomb | TN | Franklin | 2020 | OF | 2022 | 5 | Guardians |
| Will Mabrey | TN | Upperman | 2019 | LHP | 2022 | 6 | Diamondbacks |
| Christopher McElvain | TN | Summit | 2019 | RHP | 2022 | 8 | Reds |
| Hayden Mullins | TN | Hendersonville | 2019 | LHP | 2022 | 12 | Red Sox |
| Luke Murphy | TN | East Robertson | 2018 | RHP | 2021 | 4th | Los Angeles Angels |
| Duncan Pence | TN | Farragut | 2016 | SS | 2016 | 33 | Mets |
| Kobe Robinson | TN | Alcoa | 2019 | RHP | 2021 | 13 | Padres |
| Ryan Rolison | TN | University School of Jackson | 2016 | LHP | 2016 | 37 | Padres |
| Dalton Rushing | TN | Brighton | 2019 | C | 2022 | 2 | Dodgers |
| Grayson Saunier | TN | Collierville | 2022 | RHP | 2022 | 19 | Rangers |
| Garrett Spain | TN | Clarksville | 2018 | OF | 2021 | 15 | Blue Jays |
| Spencer Strider | TN | Christian Academy of Knoxville | 2017 | RHP | 2020 | 4th | Atlanta Braves |
| Blade Tidwell | TN | Loretto | 2020 | RHP | 2022 | 2 | Mets |
| Ryan Weathers | TN | Loretto | 2018 | LHP | 2018 | 1 | Padres |
