| Name | State | School | Class | Pos. | Year | Round | Team |
| Bryce Ball | IA | Mason City Newman Catholic | 2016 | 1B | 2019 | 24 | Braves |
| Carter Baumler | IA | Dowling Catholic | 2020 | RHP | 2020 | 5th | Baltimore Orioles |
| Jared Beck | IA | Davenport North | 2018 | LHP | 2022 | 13 | Orioles |
| Ian Bedell | IA | Davenport Central | 2018 | RHP | 2020 | 4th | St. Louis Cardinals |
| Chris Comito | IA | Norwalk | 2015 | RHP | 2015 | 15 | White Sox |
| Duncan Davitt | IA | Indianola | 2018 | RHP | 2022 | 18 | Rays |
| Alex Hoppe | IA | Unity Christian | 2017 | RHP | 2022 | 6 | Red Sox |
| Drew Irvine | IA | Waukee | 2018 | RHP | 2021 | 19th | Pittsburgh Pirates |
| Mitch Keller | IA | Xavier | 2014 | RHP | 2014 | 2 | Pirates |
| Austin Krob | IA | Lisbon | 2018 | LHP | 2022 | 12 | Padres |
| Ryan Lillard | IA | Urbandale | 2014 | SS | 2014 | 30 | Royals |
| Peyton Long | IA | WDM Valley | 2016 | RHP | 2019 | 30 | Brewers |
| Cole McDonald | IA | New Hampton | 2015 | RHP | 2019 | 15th | Astros |
| Keaton McKinney | IA | Ankeny Centennial | 2014 | RHP | 2014 | 28 | Mets |
| Ian Moller | IA | Dubuque Wahlert | 2021 | C | 2021 | 4th | Texas Rangers |
| Evan Reifert | IA | Wilton | 2017 | RHP | 2018 | 30 | Texas Rangers |
| TJ Sikkema | IA | Central Dewitt | 2016 | LHP | 2019 | 38th Overall Pi | Yankees |
| Tommy Specht | IA | Wahlert Catholic | 2022 | OF | 2022 | 6 | Rangers |
| Brady Stover | IA | Collins- Maxwell-Baxter | 2016 | LHP | 2019 | 31 | Nationals |
| John Swanda | IA | Des Moines Roosevelt | 2017 | RHP | 2017 | 4 | Angels |
| Daniel Tillo | IA | Sioux City North | 2015 | LHP | 2015 | 39 | Twins |
| Levi Usher | IA | Cedar Rapids Prairie | 2018 | OF | 2022 | 10 | Royals |
| Spencer Van Scoyoc | IA | Cedar Rapids Jefferson | 2016 | LHP | 2019 | 19 | Phillies |
| Connor Van Scoyoc | IA | Cedar Rapids Jefferson | 2018 | RHP | 2018 | 11th | Angels |
| Trenton Wallace | IA | Davenport Assumption | 2017 | LHP | 2021 | 11th | Toronto Bluejays |
| Peyton Williams | IA | Johnston | 2019 | 1B | 2022 | 7 | Blue Jays |
| Keaton Winn | IA | Pekin | 2016 | RHP | 2017 | 20 | Giants |
| Malique Ziegler | IA | Des Moines East | 2014 | OF | 2016 | 22 | Giants |